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Updated: Sep 29, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endonasal sinus surgery: extended versus limited approach
Matthias Kuehnemund1, Andrej Lopatin, Ronald G Amedee
1Department of Otorhinolaryngology, Head and Neck Surgery, University of Mainz, School of Medicine, Germany.
Background:
This study was designed to investigate whether two different surgical approaches in endonasal sinus surgery lead to different postoperative results in patients with chronic rhinosinusitis.
Methods:
Sixty-five patients suffering from chronic rhinosinusitis were operated on with either a limited approach or an extended approach. They were examined preoperatively and reassessed during 3 months, 6 months, and long-term follow-up visits that included endoscopy, saccharin transport time, and the assessment of symptoms.
Results:
The concept of this study was prospective, randomized, and multicenter (Mainz, Germany, and Moscow, Russia). The results of the two different surgical approaches were compared with each other.
Conclusion:
Surgical results and symptomatology were similar in both groups of patients, suggesting that a conservative approach may be sufficient in most patients.
