An artificial guanine that binds cytidine through the cooperative interaction of metal coordination and hydrogen
1Department of Chemistry, University of Toronto, 80 St. George St., Toronto, Ontario, Canada M5S 3H6.
Journal of the American Chemical Society
|September 13, 2002
Abstract:
Cd(II) complex of L binds selectively to cytidine in DMSO with an equilibrium constant of 117 M-1 (where LH is 2-aminomethyl-8-hydroxyquinoline). In contrast, the Zn(II) complex of L does not bind appreciably to any of the four nucleobases under the same condition used for the Cd(II) complex.
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