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Comparison between high-resolution helical CT and pathology in breast examination
1Division of Diagnostic Radiology, Shizuoka Cancer Center Hospital, Shizuoka and Divisions of Surgery and Pathology, Niigata Cancer Center Hospital, Niigata, Japan.
Acta Radiologica (Stockholm, Sweden : 1987)
|September 13, 2002
Summary
High-resolution helical CT can accurately identify non-breast cancer lesions (non-BCLE) by showing architectural features. This imaging technique improves the accuracy of breast cancer local staging when compared to histology.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Accurate staging of breast cancer is crucial for effective treatment planning.
- Non-breast cancer lesions (non-BCLE) require precise identification to avoid overtreatment.
Purpose of the Study:
- To evaluate the capability of high-resolution helical CT in visualizing the architectural characteristics of non-BCLE.
- To define the characteristic CT morphology of non-BCLE.
Main Methods:
- Prospective study of 136 invasive breast carcinomas using high-resolution helical CT prior to breast-conserving surgery.
- Definition of non-BCLE based on distance from the dominant mass and enhancement patterns on CT.
- Correlation of CT findings with gross morphology and histology post-resection.
Main Results:
- Non-BCLE were identified in 47 invasive carcinomas.
- High-resolution helical CT demonstrated 70% sensitivity and 89% specificity for non-BCLE detection.
- CT morphology of non-BCLE correlated well with histologic findings and intraductal tumor density.
Conclusions:
- High-resolution helical CT can effectively demonstrate the morphology of non-BCLE.
- Incorporating CT findings with histologic data enhances the accuracy of breast carcinoma local staging.