Some clinical and immunological aspects on contracted kidney in cats

With four clinical cases of contracted kidney in cats, granular to linear depositions of IgG and beta1C were demonstrated mainly in the capillary walls and mesangium of the glomeruli by means of immunofluorescence technique. The tubular basement membrane was also positive for cat IgG. These findings indicated that some immunological mechanisms might have been involved in the feline advanced renal lesions, as suggested in human cases. However, attempts were failed to detect some pathogenic agents for cats by immunofluorescence studies.