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Inducible AmpC beta-lactamase of a new member Enterobacteriaceae
Richard Bonnet1, Catherine Chanal, Elisabeth Ageron
1Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont-Ferrand Cedex, France. richard.bonnet@u-clermont1.fr
Antimicrobial Agents and Chemotherapy
|September 18, 2002
Abstract:
Extensive biochemical testing and 16S rRNA and rpoB sequence analysis revealed that clinical strain CF01Ent1, initially identified as Buttiauxella agrestis by the use of Api 32 biochemical strips, is a new organism in the Enterobacteriaceae family. It produced an inducible AmpC-type beta-lactamase whose sequence shares 69 to 72% identity with those of the other AmpC-type beta-lactamases of ENTEROBACTERIACEAE: This enzyme exhibits an atypical high affinity for all beta-lactams tested.