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Updated: Jul 30, 2026

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
Published on: April 14, 2011
[Scientigraphic hot lesions secondary to osseous metastases in a patient with multiple myeloma]
G Ruiz Hernández1, C Vázquez Forner, M V Fliquete Peris
1Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, Spain. focuscan@teleline.es
Abstract:
The myeloma bone deposits may be normal or may also appear as areas of a low uptake on the bone scintigraphy; the presence of multiple hot lesions with negative X-ray and minimal CT findings in patients with multiple myeloma being very uncommon. We reported the case of a 68 year old woman suffering from a multiple myeloma with multiple and hot metastatic lesions in bone scintigraphy. The X-ray was negative and the CT-findings only demonstrated a lytic femoral lesion, the spinal osseous dissemination being confirmed by MRI. We believe that this is an interesting work due to the rarity of the scintigraphic pattern as well as the discussion carried out on the radionuclide imaging methods in the diagnosis of myeloma-related bone lesions.
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