Reversible hemiparesis associated with the use of topiramate
Hema Patel1, Jorge J Asconapé, Bhuwan P Garg
1Section of Child Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Seizure
|September 19, 2002
Abstract:
We report a case of a 5-year-old boy with intractable partial seizures who developed a transient hemiparesis, worsening of the electroencephalogram (EEG) and a change in his seizure pattern with increased seizure frequency after receiving topiramate (TPM). Symptoms resolved within a month after TPM was discontinued. Clinicians need to be aware that TPM use may occasionally be associated with focal motor weakness and exacerbation of seizures.
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