Clinical and morphological correlations in mesangial glomerulonephritis in children

The present series comprises 36 cases of mesangial glomerulonephritis in children aged from six months to 14 years. On the basis of morphological criteria, types with considerable and slight mesangial proliferation were distinguished. Slight mesangial proliferation was more typical of younger children. Clinically they showed more often the nephrotic syndrome (sometimes difficult to differentiate from lipoid nephrosis). Older children developed mesangial proliferation rather of greater intensity: renal insufficiency and erythruria predominated in this group.