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Blood salvage with a continuous autotransfusion system compared with a haemofiltration system
N Nitescu1, A Bengtsson, J P Bengtson
1Department of Anaesthesiology and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden. nicoletta.nitescu@vgregion.se
Perfusion
|September 24, 2002
Summary
Haemofiltration (HF) offers superior recovery of blood components like leucocytes and platelets compared to continuous centrifugation (CATS) during intraoperative autotransfusion, with minimal red blood cell destruction by either method.
Area of Science:
- Biomedical Engineering
- Transfusion Medicine
- Cellular Biology
Background:
- Intraoperative blood salvage aims to reinfuse a patient's own blood.
- Autotransfusion processing can lead to red blood cell destruction.
- Evaluating component recovery is crucial for optimizing salvage techniques.
Purpose of the Study:
- Compare blood component recovery rates between continuous centrifugation and washing (CATS) and haemofiltration (HF) methods.
- Assess the efficiency of two autotransfusion processing techniques.
- Determine the optimal method for preserving blood components during intraoperative salvage.
Main Methods:
- Randomized laboratory study comparing CATS and HF using donor whole blood.
- Activated whole blood was processed through either centrifugation or a 30,000-Da filter.
- Measured recovery rates for red blood cells, haemoglobin, leucocytes, platelets, albumin, total protein, and potassium.
Main Results:
- Red blood cell recovery was 86% for CATS and 76% for HF.
- HF demonstrated significantly higher recovery of leucocytes (63% vs. 20%), platelets (37% vs. 4%), albumin (70% vs. 0.2%), total protein (71% vs. 1.3%), and potassium (17% vs. 2%).
- Both methods resulted in less than 1% haemolysis.
Conclusions:
- Both autotransfusion methods minimize red blood cell destruction.
- Haemofiltration (HF) provides superior recovery of leucocytes, platelets, albumin, total protein, and extracellular potassium compared to the CATS method.
- HF is a more effective technique for preserving a wider range of blood components during intraoperative salvage.