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A new rotary blood pump for versatile extracorporeal circulation: the DeltaStream
1Helmholtz Institute for Biomedical Engineering, Aachen University of Technology, Germany.
Perfusion
|September 24, 2002
Summary
The novel DeltaStream miniaturized rotary blood pump offers flexible extracorporeal circulation and ventricular assist device applications. Animal studies confirm its biocompatibility, hydraulic capacity, and reduced haemolysis for improved patient outcomes.
Area of Science:
- Biomedical Engineering
- Cardiovascular Technology
Background:
- Rotary pumps are standard for extracorporeal circulation but have limitations.
- Existing pumps face challenges in miniaturization, haemolysis, and thrombogenicity.
- A need exists for advanced pumps in ventricular assist and extracorporeal life support.
Purpose of the Study:
- To introduce the DeltaStream, a novel miniaturized rotary blood pump.
- To evaluate its hydraulic capacity, biocompatibility, and haemocompatibility.
- To assess its suitability for extracorporeal circulation, VAD, and ECLS applications.
Main Methods:
- Design and development of the miniaturized DeltaStream pump with an integrated drive unit.
- Optimization of impeller design for reduced haemolysis and non-thrombogenicity.
- In vitro and in vivo testing, including seven animal experiments.
Main Results:
- The DeltaStream demonstrated sufficient hydraulic capacity for flexible intra- and perioperative use.
- Optimized impeller design minimized haemolysis and thrombogenicity.
- Animal studies confirmed the pump's biocompatibility and applicability in extracorporeal circulation and VAD simulation.
Conclusions:
- The DeltaStream is a versatile miniaturized rotary blood pump suitable for various clinical applications.
- Its design offers improved haemocompatibility and physiological simulation compared to existing pumps.
- The DeltaStream shows promise for short-term VAD and ECLS systems.