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Updated: Aug 9, 2026

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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Single ventricle, total transposition, and hypoplastic aorta in a calf
Veterinary Pathology
|September 24, 2002
Summary
A rare congenital heart defect case in an Ayrshire calf involved a single ventricle, aorta transposition, and other severe cardiac anomalies. This unique combination, previously undescribed in domestic animals, led to the calf
Area of Science:
- Veterinary Cardiology
- Congenital Malformations
- Animal Genetics
Background:
- Congenital cardiac defects are significant causes of mortality in young animals.
- Ayrshire cattle are a breed known for specific genetic predispositions.
Observation:
- A purebred Ayrshire calf presented with a complex set of multiple congenital cardiac defects.
- The calf exhibited absence of the interventricular septum (single ventricle), transposition of the great arteries, interatrial septal defect, patent ductus arteriosus, and aortic arch anomalies.
Findings:
- This specific constellation of severe cardiac malformations is novel and has not been previously documented in veterinary literature.
- Despite the critical nature of the defects, the calf survived for five days post-birth.
Implications:
- This case highlights the potential for unique and complex congenital cardiac defects to arise in purebred animals.
- Further research into the genetic and developmental factors underlying such anomalies is warranted.
- Understanding these defects is crucial for veterinary diagnostics and potential breeding strategies.

