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[Clinico-pharmacological studies with Nifedipine--a new coronary substance]
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|September 1, 1975
Abstract:
On 19 test persons (10 healthy persons, 9 patients with heart diseases) mechanocardiographic and haemodynamic examinations were carried out with the new preparation Nifedipine (05-072) which effects on the coronary vessels. Insignificant positively inotropic effects with invariable heart rate and cardiac output, decreasing heart action and decreased oxygen consumption were found. Arterial blood pressure and peripheral resistance were only slightly diminished. Own results and reports from literature show that the application of Nifedipine in the ischaemic heart disease appears to be successful.