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Who discovered the Frank-Starling mechanism?
1Carl-Ludwig-Institute of Physiology, University of Leipzig, D-04103 Leipzig, Germany.
Abstract:
In 1866 at Carl Ludwig's Physiological Institute at Leipzig, Elias Cyon described the influence of diastolic filling of the isolated perfused frog heart on ejection volume. A study performed at the institute of the effect of filling pressure on contraction amplitude was published in 1869 by Joseph Coats, based on a recording made by Henry P. Bowditch.