An improved method for measuring the size of myocardial infarctions

A new method is proposed for the estimation of infarction size from several measurements of creatine phosphokinase (CPK) activity. This method develops the previous method of Shell and co-workers by introducing the concept of a time- dependent fractional disappearance rate for CPK (kd(t) from the blood. This method would allow more accurate estimates to be made of infarction size.