[Gonadotropic hormone excretion in men with hypogonadism and its dynamics under the influence of exogenous...

The work is a clinico-laboratory study and and treats of the results of determination of gonadotropine excretion before and after the administration of testosterone to the patients with various forms of hypogonadism. The prevailing effect of testosterone on the excretion of the gonadotropic hormones could be blocking, stimulating or neutral depending on the clinical variant of hypogonadism. Thus, a change of sensitivity of the central link in the hypophysis-gonad system to the action of the peripheral hormones could apparently be of definite significance in the pathogenesis of hypogonadism; this should be taken into consideration in the elaboration of rational schemes of its therapy.