[The interrelationship between histologic and ultrastructural changes in the liver in the presence of pathologic...

A study was made of liver cells of cirrhosis-affected patients and those with portal hypertensia due to subhepatic block. It was shown that the extent of cellular injury was directly related to the pattern of pathological process in the liver. In the case of active cirrhosis, the necrobiotic processes observed might be due to changes in the structures providing cellular metabolism. With stable cirrhosis, the changes observed suggest abnormalities in cell synthesis, in addition to the rise in aerobic respiration. The analysis of the data obtained in the cases of subhepatic block without cirrhosis showed a sufficient functional activity of liver cells.