Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatty acid ethyl esters: recent observations.

Michael Laposata1, Ali Hasaba, Catherine A Best

  • 1Department of Pathology, Division of Laboratory Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. mlaposata@partners.org

Prostaglandins, Leukotrienes, and Essential Fatty Acids
|September 27, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prophylactic half-dose platelet transfusion effect on thrombocytopenia, transfusion, and bleeding occurrence in patients with hematologic disease.

American journal of clinical pathology·2026
Same author

Differences in outcomes associated with ABO blood groups in recipients of IVIG.

Blood vessels, thrombosis & hemostasis·2025
Same author

Role of <i>TERT</i> gene mutation in the pathogenesis of anaplastic thyroid carcinoma (Review).

Molecular and clinical oncology·2025
Same author

Four-Factor Prothrombin Complex Concentrate vs Plasma in Patients on Vitamin K Antagonists With Gastrointestinal Bleeding or Needing a Gastrointestinal Procedure: A Retrospective Analysis of 2 Randomized Controlled Trials.

Journal of the American College of Emergency Physicians open·2025
Same author

Eliminating leukocyte reduction for whole blood: Is it premature to consider this paradigm-changing practice?

Transfusion·2024
Same author

Gender Differences in Coronary Artery Disease Severity and Revascularisation in Patients Referred for Coronary Angiography From Rural and Remote Western Australia.

Heart, lung & circulation·2024

Fatty acid ethyl esters (FAEE) are markers of ethanol intake and can cause cell injury. Ethyl oleate levels may help distinguish chronic alcoholics from binge drinkers.

Area of Science:

  • Biochemistry
  • Toxicology
  • Cardiology

Background:

  • Fatty acid ethyl esters (FAEE) are formed from fatty acids and ethanol.
  • FAEE are mediators of ethanol-induced cell injury.
  • FAEE presence in blood and tissues indicates ethanol consumption.

Purpose of the Study:

  • Investigate FAEE generation during cardiac ablation.
  • Explore the role of FAEE in myocyte death during cardiac procedures.
  • Assess the utility of ethyl oleate levels in differentiating alcohol consumption patterns.

Main Methods:

  • Ethanol infusion protocols similar to myocardial ablation.
  • Analysis of FAEE production in cardiac tissue.
  • Measurement of serum ethyl oleate concentrations.

Related Experiment Videos

Main Results:

  • FAEE are rapidly produced within seconds of ethanol infusion into the heart.
  • Toxic FAEE generation is a potential mechanism for myocyte death in cardiac ablation.
  • Chronic alcoholics exhibit high concentrations of ethyl oleate.

Conclusions:

  • FAEE play a role in ethanol-induced cardiac injury.
  • Serum ethyl oleate concentration can differentiate chronic alcoholics from binge drinkers.