Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Somatotropic hormone].

B Boscherini

    Annali Dell'Istituto Superiore Di Sanita
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Accurate diagnosis of hypopituitary dwarfism is crucial. Testing human growth hormone (HGH) levels under fasting and stimulation conditions helps differentiate causes, ensuring effective HGH therapy for deficient secretion only.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Early retesting by GHRH + arginine test shows normal GH response in most children with idiopathic GH deficiency.

    Journal of endocrinological investigation·2014
    Same author

    Unequal access, low vaccination coverage, growth retardation rates among immigrants children in Italy exacerbated in Roma immigrants.

    Minerva pediatrica·2014
    Same author

    Molecular characterization of 6 unrelated Italian patients with 5alpha-reductase type 2 deficiency.

    Journal of andrology·2007
    Same author

    Urinary excretion of pyridinium crosslinks in short children treated with growth hormone.

    Journal of pediatric endocrinology & metabolism : JPEM·2002
    Same author

    Long-term treatment with growth hormone improves final height in a patient with Pallister-Hall syndrome.

    American journal of medical genetics·2001
    Same author

    Growth and insulin-like growth factors (IGFs) in children with insulin-dependent diabetes mellitus at the onset of disease: evidence for normal growth, age dependency of the IGF system alterations, and presence of a small (approximately 18-kilodalton) IGF-binding protein-3 fragment in serum.

    The Journal of clinical endocrinology and metabolism·2000
    Same journal

    External quality assessment programs in cytogenomics in the Lombardy Region, Italy (2018-2024): performance and trends.

    Annali dell'Istituto superiore di sanita·2026
    Same journal

    Spontaneous orienting of untrained companion dogs naïve to human epilepsy toward odor samples from an unfamiliar human in a controlled non-social paradigm: a proof-of-concept.

    Annali dell'Istituto superiore di sanita·2026
    Same journal

    Addressing food and nutrition insecurity in European countries: a scoping review of strategies and policies.

    Annali dell'Istituto superiore di sanita·2026
    Same journal

    Women's experiences of membrane sweeping for labour induction: a phenomenological qualitative study.

    Annali dell'Istituto superiore di sanita·2026
    Same journal

    Evaluating the usefulness of the Mediterranean Diet Quality Index (KIDMED) in assessing eating habits and nutritional status among preschool children.

    Annali dell'Istituto superiore di sanita·2026
    Same journal

    Optimizing sample preparation for homogeneous mycotoxin distribution in official control analyses.

    Annali dell'Istituto superiore di sanita·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Pediatric Endocrinology
    • Growth Hormone Disorders

    Background:

    • Human growth hormone (HGH) is vital for development.
    • Deficient HGH secretion can cause hypopituitary dwarfism.
    • Accurate diagnosis is essential due to limited HGH availability.

    Purpose of the Study:

    • To outline the diagnostic process for suspected HGH deficiency.
    • To differentiate between various causes of hypopituitary dwarfism.
    • To emphasize the importance of precise diagnosis for effective HGH therapy.

    Main Methods:

    • HGH level measurement in fasting (basal) and stimulated conditions.
    • Evaluation of laboratory data alongside clinical information.
    • Exclusion of other growth-retarding factors before HGH testing.

    Related Experiment Videos

    Main Results:

    • Distinguishes between HGH deficiency and peripheral resistance.
    • Identifies cases of hypopituitary dwarfism amenable to HGH therapy.
    • Highlights the necessity of comprehensive testing for accurate diagnosis.

    Conclusions:

    • Reliable diagnosis of hypopituitary dwarfism type is necessary.
    • HGH therapy is effective solely for deficiency-induced nanism.
    • Accurate diagnostic protocols ensure appropriate patient management and treatment.