Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Adequate dialysis (author's transl)].

B H Scribner

    L'Ateneo Parmense. Acta Bio-Medica : Organo Della Societa Di Medicina E Scienze Naturali Di Parma
    |September 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Peritoneal dialysis patients show no peripheral neuropathy, suggesting the peritoneal membrane removes larger toxic solutes than cuprophane. Small molecule accumulation is safe, but middle molecule toxicity remains unproven.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sodium, not fluid, controls interdialytic weight gain.

    Nephrology news & issues·2002
    Same author

    Rationing dialysis: the early years.

    Seminars in dialysis·2000
    Same author

    Scribner: we need to do better.

    Nephrology news & issues·2000
    Same author

    BP control, dialysis adequacy, and vitamin C.

    Seminars in dialysis·2000
    Same author

    Can antihypertensive medications control BP in haemodialysis patients: yes or no?

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1999
    Same author

    Chronic hemodialysis using venipuncture and a surgically created arteriovenous fistula. 1966.

    Journal of the American Society of Nephrology : JASN·1999
    Same journal

    [The effect of Deanol on amnesic disorders. A preliminary trial (author's transl)].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    Same journal

    [The pregnancy in women above 40 years (author's transl)].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    Same journal

    [Combination of althesin and fentanyl as an alternative anesthetic in burns].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    Same journal

    [Adolescent pregnancy (author's transl)].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    Same journal

    [Intrahepatic cholestasis and fetal prognosis (author's transl)].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    Same journal

    [Fine structure of pineal gland in some Chiroptera. (Vesperugo savi and Rinolophus f.e.). I. Histochemical and ultrastructural study (author's transl)].

    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma·1980
    See all related articles

    Area of Science:

    • Nephrology
    • Biomedical Engineering

    Context:

    • Peripheral neuropathy is absent in peritoneal dialysis (PD) patients.
    • This observation suggests the peritoneal membrane's unique solute removal properties compared to other dialysis membranes like cuprophane.
    • Investigating dialysis strategies is crucial for patient well-being.

    Purpose:

    • To explore the hypothesis that the peritoneal membrane removes larger toxic solutes than cuprophane.
    • To evaluate the significance of residual renal function and reduced dialysis schedules.
    • To assess the clinical implications of solute accumulation in dialysis patients.

    Summary:

    • The study investigated
    • in vitro
    • and
    • in vivo

    Related Experiment Videos

  • dialysis strategies.
  • A trial involving 7 patients, one treated for 20 months, examined residual renal function and reduced dialysis schedules.
  • Findings suggest that small molecule accumulation, within limits, is not detrimental, while middle molecule toxicity lacks definitive evidence in dialysis patients.

    • Impact:

    • Provides insights into the solute transport characteristics of the peritoneal membrane.
    • Informs the optimization of dialysis strategies, including reduced schedules and the role of residual renal function.
    • Contributes to understanding the safety of small molecule accumulation and the unproven middle molecule hypothesis in dialysis therapy.