Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Elective single day 3 embryo transfer halves the twinning rate without decrease in the ongoing pregnancy rate of an

Jan Gerris1, Diane De Neubourg, Katelijne Mangelschots

  • 1Center for Reproductive Medicine, Middelheim Hospital, Lindendreef 1, 2020 Antwerp, Belgium. jan.gerris@ocmw.antwerpen.be

Human Reproduction (Oxford, England)
|September 28, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A drop in serum estradiol levels during GnRH antagonist cotreatment in cycles stimulated with gonadotropins is associated with lower cumulative live birth rates.

Frontiers in endocrinology·2026
Same author

Misleading messages from the web: professional medical counseling and public datasets vs. online health information in in vitro fertilization.

Fertility and sterility·2026
Same author

Reply: Iatrogenic breaching of the junctional zone: the unintended path to placenta accreta spectrum?

Facts, views & vision in ObGyn·2025
Same author

Intrauterine application of Budesonide-hyaluronic acid gel in patients with recurrent implantation failure and total loss of junctional zone differentiation on magnetic resonance imaging.

Facts, views & vision in ObGyn·2025
Same author

Stepwise approach of hysteroscopic cytoreductive surgery for adenomyosis in patients with recurrent implantation failure.

Fertility and sterility·2024
Same author

A blended preconception lifestyle programme for couples undergoing IVF: lessons learned from a multicentre randomized controlled trial.

Human reproduction open·2024

Elective single embryo transfer (eSET) can significantly reduce multiple pregnancies in IVF programs. This study shows that careful application of eSET effectively lowers twinning rates while preserving overall pregnancy success rates.

Area of Science:

  • Reproductive Medicine
  • In Vitro Fertilization (IVF)
  • Embryo Transfer Techniques

Background:

  • Assessing the impact of elective single embryo transfer (eSET) on pregnancy outcomes in IVF/ICSI programs.
  • Evaluating the effect of eSET on total and multiple pregnancy rates.

Purpose of the Study:

  • To analyze the effectiveness of elective single embryo transfer (eSET) in reducing multiple pregnancies.
  • To determine if eSET impacts overall pregnancy rates in IVF/ICSI cycles.

Main Methods:

  • Retrospective cohort analysis of 1559 IVF/ICSI cycles over a 4-year period.
  • Comparison of pregnancy and twinning rates between single and multiple embryo transfers.
  • Tracking changes in embryo transfer practices and outcomes from 1998 to 2001.

Related Experiment Videos

Main Results:

  • Elective single embryo transfer (eSET) resulted in ongoing pregnancy rates of 35.1% for top-quality embryos and 22.1% for non-top-quality embryos.
  • Multiple embryo transfers (2 or more) yielded an ongoing pregnancy rate of 33.9%.
  • Over four years, the average ongoing pregnancy rate was 33.5% per transfer, while multiple and twinning rates decreased from 33.6% and 29.5% to 18.6% and 16.3% respectively.

Conclusions:

  • Judicious application of elective single embryo transfer (eSET) can effectively halve twinning rates.
  • eSET allows for the maintenance of overall pregnancy rates in IVF/ICSI programs.
  • This strategy balances the reduction of multiple gestations with sustained fertility treatment success.