Intracameral amphotericin B injection in the management of deep keratomycosis
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Published on: June 13, 2018
Thomas Kuriakose1, Mihir Kothari, Padma Paul
1Schell Eye Hospital, Department of Ophthalmology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India. thomask@cmcvellore.ac.in
Purpose:
To report the use of intracameral amphotericin B in the management of deep keratomycosis.
Methods:
Four patients with deep keratomycosis unresponsive to conventional medical treatment underwent repeated intracameral injections of 5 microg amphotericin B in 0.1 mL 5% dextrose through a paracentesis. Three to 13 intracameral injections were given to each patient over 6 to 36 days.
Results:
Three of the four patients had complete resolution of the ulcer. The fourth patient perforated and required evisceration.
Conclusion:
Preliminary experience suggests that intracameral injections of amphotericin B may have a role in the management of deep keratomycosis.
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