[Drug lesions of the gastroduodenal zone]

Many new high effective preparations, acting on cellular and molecular levels, now have appeared. They have rendered more penetrating influences on the various aspects of the organism activity and causing thus the side effects. They are the following: medicine-induced disorders of stomach and duodenum at treatment by nonsteroid anti-inflammation preparations accompanying by development of erosions, ulcers and bleeding, exacerbations of chronic ulcers and etc. The medicine-induced disorders of the digestive organs recently began to determine as the nosologic forms with possible acute and chronic current. Even lethal cases are observed at using medicines in medical doses. Till now there are no legible criteria of clinical-laboratory and morphological diagnostics of medicine-induced disorders of the digestive organs. The problems of their pathogenesis are studied insufficiently. There is no united classification. In this connection, the purpose of the given article is the study of epidemiology, pathogenesis, features of diagnostics and clinical current of medicinal gastropathies.