Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The zebrafish eye: developmental and genetic analysis.

Stephen S Easter1, Jarema J Malicki

  • 1Dept. of Molecular, Cellular, and Developmental Biology, University of Michigan, 830N. University Ave., Ann Arbor, Michigan 48109-1048, USA.

Results and Problems in Cell Differentiation
|October 2, 2002
PubMed
Summary
This summary is machine-generated.

Zebrafish eye development shares similarities with other vertebrates and flies. New insights into optic vesicle proliferation, neurogenesis, and retinal stratification offer valuable applications for vertebrate eye development research.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena.

Scientific reports·2022
Same author

Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia.

Frontiers in cell and developmental biology·2021
Same author

Ciliopathy genes are required for apical secretion of Cochlin, an otolith crystallization factor.

Proceedings of the National Academy of Sciences of the United States of America·2021
Same author

STORM imaging reveals the spatial arrangement of transition zone components and IFT particles at the ciliary base in Tetrahymena.

Scientific reports·2021
Same author

Identification of additional outer segment targeting signals in zebrafish rod opsin.

Journal of cell science·2021
Same author

The Nuclear Arsenal of Cilia.

Developmental cell·2019

Area of Science:

  • Developmental Biology
  • Ophthalmology
  • Genetics

Background:

  • Zebrafish eye development serves as a model organism for studying vertebrate ocular development.
  • Previous research has established commonalities between zebrafish and other species' eye development.

Purpose of the Study:

  • To review major aspects of zebrafish eye development.
  • To highlight novel insights from zebrafish research applicable to other vertebrates.
  • To discuss the genetic and cellular mechanisms governing eye development.

Main Methods:

  • Literature review of existing studies on zebrafish eye development.
  • Comparative analysis of zebrafish eye development with other vertebrates and Drosophila.
  • Synthesis of findings related to cellular proliferation, neurogenesis, photoreceptor patterning, cell fate determination, and retinal stratification.

Main Results:

  • Zebrafish eye development largely mirrors that of other vertebrates and the fly.
  • Identified key insights including modulated optic vesicle cellular proliferation and complex retinal neurogenesis.
  • Detailed the emergence of spatial order in photoreceptors and genetic controls of cell fates and retinal stratification.

Conclusions:

  • Zebrafish provide crucial, novel insights into vertebrate eye development.
  • Further research, accelerated by genomics and the zebrafish genome project, will expand understanding.
  • Findings have significant implications for understanding and potentially treating human eye conditions.