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Reduction of contamination of mycobacterial growth indicator tubes with a modified antimicrobial combination
Chulhun Ludgerus Chang1, Tae Sung Park, Seung Hwan Oh
1Department of Clinical Pathology, College of Medicine, Pusan National University, #10 1-Ga Ami-Dong Seo-Gu, Pusan 602-739, Korea. cchl@pusan.ac.kr
Journal of Clinical Microbiology
|October 2, 2002
Abstract:
Culture in the fluorimetric Mycobacteria Growth Indicator Tube (MGIT) treated with a combination of vancomycin, amphotericin B, and nalidixic acid (VAN) showed growth of most strains of 31 mycobacterial species with a less-than-1-day delay. The results were similar to those in the MGIT with polymyxin B, amphotericin B, nalidixic acid, trimethoprim, and azlocillin, but with respiratory specimens, the MGIT with VAN showed a lower contamination rate with no change in the detection rate or time.