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Related Experiment Videos

[Anaphylactic shock revealing anisakiasis].

Jean-François Magnaval1, Antoine Berry, Michel Nadrigny

  • 1Laboratoire de parasitologie, CHU Rangueil, 31403 Toulouse. magnaval@cict.fr

Presse Medicale (Paris, France : 1983)
|October 3, 2002
PubMed
Summary

Anisakiasis, a parasitic infection from raw fish, can cause severe allergic reactions like anaphylaxis. Prompt diagnosis via serology and treatment with albendazole are crucial for recovery.

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Area of Science:

  • Medical Parasitology
  • Clinical Immunology
  • Gastroenterology

Background:

  • Anisakiasis often presents with digestive symptoms or complications like ileal obstruction.
  • Recent literature highlights allergic manifestations, including anaphylaxis, associated with this helminthic zoonosis.
  • Early or asymptomatic cases can be revealed by severe allergic reactions.

Observation:

  • A 60-year-old male experienced anaphylactic shock and diarrhea after consuming tuna.
  • Delayed symptoms included fatigue, cough, and rashes, with borderline hypereosinophilia and elevated IgE.
  • Initial diagnosis of histamine shock was revised to anisakiasis based on positive serology.

Findings:

  • Highly positive anisakiasis serology confirmed the diagnosis in a patient presenting with anaphylaxis.
  • Treatment with albendazole (10 mg/kg/day for 7 days) led to excellent clinical and biological recovery.
  • Serological confirmation is key, especially when allergic reactions are present after fresh fish consumption.

Implications:

  • Investigate fresh fish ingestion in patients with allergic reactions, even minor ones.
  • Anisakiasis immunodiagnosis is recommended if fresh fish consumption is reported.
  • Seropositive cases require confirmation via endoscopy; anthelminthic treatment is advised even if larvae are not found.

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