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Panic attacks associated with citalopram.

Heidi R Brauer1, Paul W Nowicki, Glenn Catalano

  • 1Department of Psychiatry and Behavioral Medicine, University of South Florida College of Medicine, Tampa 33613, USA.

Southern Medical Journal
|October 3, 2002
PubMed
Summary
This summary is machine-generated.

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Selective serotonin reuptake inhibitors (SSRIs) like citalopram can induce panic attacks. This case report details a patient experiencing panic attacks after a citalopram dose increase, with symptoms resolving upon discontinuation.

Area of Science:

  • Pharmacology
  • Psychiatry
  • Clinical Case Reports

Background:

  • Selective serotonin reuptake inhibitors (SSRIs) are widely used for major depression.
  • Citalopram, a newer SSRI, is FDA-approved for depression and shows efficacy in panic disorder.
  • Panic attacks induced by SSRIs have been reported, but not previously with citalopram.

Observation:

  • A 61-year-old woman with no prior anxiety history developed distinct panic attacks.
  • These panic attacks emerged after her prescribed citalopram dosage was elevated.
  • The patient's anxiety symptoms completely resolved once citalopram treatment was stopped.

Findings:

  • This case presents the first report of citalopram potentially inducing panic attacks.
  • The temporal relationship suggests a possible causal link between increased citalopram dose and panic attacks.

Related Experiment Videos

  • Discontinuation of citalopram led to the complete resolution of panic symptoms.

    • Implications:

    • Clinicians should be aware of the potential for citalopram to induce panic attacks, even in patients without prior anxiety.
    • This finding warrants further investigation into the paradoxical effects of SSRIs.
    • Careful dose titration and patient monitoring are crucial when initiating or increasing citalopram therapy.