Related Experiment Video
Updated: Sep 29, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Computer simulation of the inverse problem of electrocardiography: use of properties of harmonic functions
1Biomedical Imaging Laboratory, 21 Heng Mui Keng Terrace, 119613, Singapore. belov@lit.org.sg
Abstract:
The problem of reconstructing the pattern of heart excitation from body surface potentials is simulated. The problem is well known as the inverse problem of electrocardiography and in a general case this problem has a non-unique solution. The relationship of the problem with the inverse problem of potential theory is shown. From this relationship a new excitation propagation model for the heart ventricles is developed. The model is based on a classical multidipole cardiogenerator, but is stable, flexible, and provides a unique solution for the inverse problem of electrocardiography.
Related Concept Videos
Bode Plots Construction
Linear Approximation in Frequency Domain
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear.
Properties of Fourier series II
A function f(t) is...
Instrumentation Amplifier
To overcome this challenge, an ECG machine utilizes an instrumentation amplifier. This specialized amplifier is...
Electrocardiogram
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Network Function of a Circuit

