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Cardioactive diterpenes from the roots of Salvia eriophora
Ayhan Ulubelen1, Hüsniye Birman, Sevil Oksüz
1University of Istanbul, Faculty of Pharmacy, Department of Chemistry, Istanbul, Turkey. aulubelen@yahoo.com
Planta Medica
|October 3, 2002
Abstract:
From the roots of Salvia eriophora (Lamiaceae), a new compound, 4,14-dihydroxysaprorthoquinone, was isolated in addition to ten known diterpenoids. The structure of the new compound was established by spectroscopic analysis. The crude extract of the plant and the isolated diterpenoids were tested for their cardiovascular activities using Wistar Albino rats. Activity was demonstrated in the crude extract and in 4,14-dihydroxysaprorthoquinone, aethiopinone, ferruginol, 4,12-dihydroxysapriparaquinone, and 6,7-dehydroroyleanone.