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A new anti-oedematogenic nor-pregnane derivative isolated from Mandevilla illustris
Rivaldo Niero1, Ricardo Vieira Alves, Valdir Cechinel Filho
1Núcleo de Investigações Químico Farmacêuticas, Curso de Farmácia/CCS, Universidade do Vale do Itajaí, Itajaí, SC, Brazil. neiro@ccs.univali.br
Planta Medica
|October 3, 2002
Abstract:
A new nor-pregnane derivative (2,6-dideoxy-3- O-methylpyranosylillustrol) (1), isolated from the ethyl acetate extract of Mandevilla illustris rhizomes, was identified by conventional spectral analysis and by chemical means. It markedly inhibited the rat paw oedema induced by carrageenan and, to a lesser extent, those induced by dextran, without affecting that caused by bradykinin.

