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A chemo- and stereoselective reduction of cycloalkynes to (E)-cycloalkenes
Alois Fürstner1, Karin Radkowski
1Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany. fuerstner@mpi-muelheim.mpg.de
Chemical Communications (Cambridge, England)
|October 3, 2002
Abstract:
A stereoselective entry into (E)-cycloalkenes is described, comprising the ring closing alkyne metathesis (RCAM) of suitable diynes, a ruthenium-catalyzed trans-selective hydrosilylation of the cycloalkynes thus formed, followed by a desilylation of the resulting vinylsilanes mediated by AgF.