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Effect of amiodarone on functional state of sarcoplasmic reticulum in rat myocardium

S A Afanas'ev1, I A Lukavskaya, M L Kandinskii

  • 1Research Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk.

Bulletin of Experimental Biology and Medicine
|October 3, 2002
PubMed

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The primary role of cardiac muscles is to propel blood throughout the cardiovascular system. The cardiac muscle cells, or cardiomyocytes, exhibit specialized characteristics that allow them to perform this function.
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy reserves in...