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Related Experiment Videos

Psoriasis and pregnancy.

Amanda E Tauscher1, Alan B Fleischer, Kathy C Phelps

  • 1Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

Journal of Cutaneous Medicine and Surgery
|October 4, 2002
PubMed
Summary
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Psoriasis treatment during pregnancy requires careful consideration of fetal effects. Safe options include topical corticosteroids, UVB therapy for extensive cases, and short-term cyclosporine for severe psoriasis.

Area of Science:

  • Dermatology
  • Obstetrics
  • Genetics

Background:

  • Psoriasis affects women of childbearing age, necessitating pregnancy-specific treatment considerations.
  • Understanding psoriasis heritability aids in counseling women about potential risks to offspring.
  • Psoriatic symptoms may improve during pregnancy.

Purpose of the Study:

  • To review safe and effective treatment options for psoriasis during pregnancy.
  • To guide clinical decisions regarding psoriasis management in pregnant patients.
  • To address concerns about potential fetal effects of psoriasis therapies.

Main Methods:

  • Literature review of existing studies on psoriasis treatment in pregnancy.
  • Analysis of safety data for various dermatological agents.

Related Experiment Videos

  • Evaluation of treatment efficacy based on disease severity.

    • Main Results:

    • Topical treatments like corticosteroids, calcipotriene, anthralin, and tacrolimus are suitable for localized psoriasis.
    • Ultraviolet B (UVB) phototherapy is recommended for extensive psoriasis when topical treatments are impractical.
    • Short-term cyclosporine use is considered the safest option for severe, refractory psoriasis.

    Conclusions:

    • Localized psoriasis in pregnancy can be managed with topical agents.
    • Extensive psoriasis requires UVB therapy for safety and efficacy.
    • Severe psoriasis may necessitate short-term cyclosporine under careful monitoring.