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Viral load in Epstein-Barr virus-associated hemophagocytic syndrome
Hiroshi Kimura1, Yo Hoshino, Shinya Hara
1Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan. hkimura@med.nagoya-u.ac.jp
Microbiology and Immunology
|October 5, 2002
Abstract:
The viral load in peripheral blood from patients with Epstein-Barr virus (EBV)-associated hemophagocytic syndrome was measured by real-time quantitative PCR and compared with that in infectious mononucleosis. Patients with EBV-associated hemophagocytic syndrome generally had larger viral burdens, although it was difficult to differentiate EBV-associated hemophagocytic syndrome from infectious mononucleosis simply by viral load. The difference in viral load seemed to be clearer in peripheral blood mononuclear cells than in plasma.