Differentiation between retrocorneal pseudoexfoliative material and keratic precipitates

A 62-year-old female presented with unilateral pseudoexfoliation syndrome. Apart from the classic pseudoexfoliation of the lens capsule, she also manifested conspicuous endothelial deposits of pseudoexfoliation material (PXM). The potential exists to misdiagnose endothelial deposits of PXM as keratic precipitates (KP). This patient was subsequently erroneously diagnosed with Fuchs' heterochromic cyclitis. Close inspection of the endothelial deposits should allow for appropriate differentiation between PXM and KP, particularly when one examines them in the context of the presenting symptoms and other ocular findings. It is incumbent on the practitioner to make the appropriate diagnosis to prevent the patient undergoing unnecessary clinical investigations or therapies.