Related Experiment Videos
New HLA-A*11 allele, A*1112, identified by sequence-based typing
E Garino1, M Belvedere, M Berrino
1Transplantation Immunology, San Giovanni Battista Hospital, Turin, Italy. gmazzola@molinette.piemonte.it
Tissue Antigens
|October 9, 2002
Abstract:
In this report, we describe the identification of HLA-A*1112, a novel HLA-A*11 allele found in two Italian families. The new allele was detected during routine HLA typing by a polymerase chain reaction sequence-specific primer and was confirmed by high-resolution sequencing-based typing. The nucleotide sequences of HLA-A*1112 exons 2 and 3 are identical to HLA-A*11011 except for a single nucleotide substitution in codon 90 (GAC-->GCC).