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Updated: Aug 14, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Acute allergic reaction following contact with a spider
1Discipline of Clinical Pharmacology, University of Newcastle, Newcastle Mater Misericordiae Hospital, Level 5, Clinical Sciences Building, Edith Street, Waratah, NSW 2298, Australia. gsbite@bigpond.com
Abstract:
Allergic reactions following contact or injury from arachnids are uncommon. There have previously only been reports of urticarial reactions following contact with large spiders from the family Theraphosidae. A 55-year-old male presented to hospital with a generalised urticarial rash following contact with a spider, identified by the person as a huntsman spider (Family: Sparassidae). The spider had crawled over both his arms for a period of minutes. About 30 min later, he developed a rash on the arms which spread to the trunk. He then developed bradycardia and hypotension that required treatment with atropine, adrenaline and histamine antagonists. He recovered within 6 h and had no further problems. The early allergic reaction in this case was most likely the result of contact with the spider.
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