Epilepsy in children in Benin City, Nigeria
1Institute of Child Health, University of Benin, University of Benin Teaching Hospital, Benin, Nigeria. rogersykes@hotmail.com
Insights
Epilepsy in Nigerian children shares similarities with Western countries but has unique causes like birth asphyxia. Phenobarbitone is an effective treatment, even when initiated years after seizure onset.
Area of Science:
- Pediatrics
- Neurology
- Global Health
Background:
- Epilepsy patterns in children globally.
- Specific challenges in low-resource settings.
Purpose of the Study:
- To describe the clinical features and management of childhood epilepsy in Nigeria.
- To identify factors influencing seizure control and treatment adherence.
Main Methods:
- Retrospective case series analysis.
- Review of clinical data for pediatric epilepsy patients.
- Assessment of treatment outcomes and adherence.
Main Results:
- Birth asphyxia is a notable cause; delayed medical care seeking observed.
- Good seizure control achieved in 52.9% of children.
- Phenobarbitone demonstrated efficacy and tolerability, suitable for primary care.
Conclusions:
- Childhood epilepsy in Nigeria has distinct epidemiological features.
- Effective management is achievable with accessible antiepileptic drugs like phenobarbitone.
- Further research needed on treatment non-adherence in pediatric epilepsy.
Abstract:
The pattern of epilepsy in children in Nigeria showed little difference from that seen in children in western countries, except that birth asphyxia was relatively common as a cause and there was a longer time between onset of seizures and parents seeking medical care. It was estimated that good control of seizures was achieved in 52.9% of children, but more than a quarter attended the clinic only once or twice and the reasons for this are not known. The response to medication was less satisfactory for children under 1 year, a result consistent with most other studies. Some uncommon forms and associations of epilepsy were recognised. An EEG was not essential for management but was useful for the diagnosis of syndromes. Treatment was equally effective when commenced 5 years or more after the onset of seizures. The anti-convulsant used for most children was phenobarbitone which had to be discontinued in only two cases because of side-effects. Phenobarbitone has been successfully used to treat epilepsy by primary health workers in rural Africa and this is expected to continue in the future.
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