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Updated: Aug 1, 2026

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering
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Quantitative structure-activity relationship (QSAR) paradigm--Hansch era to new millennium

A K Debnath1

  • 1Lindsley F. Kimball Research Institute of The New York Blood Center, 310 E 67(th) Street, New York, NY 10021, USA. asim_debnath@nybc.org

Mini Reviews in Medicinal Chemistry
|October 9, 2002
PubMed
Summary

Quantitative structure-activity relationship (QSAR) analysis, initiated in the 1960s, quantitatively links molecular properties to biological activity. This review covers the evolution of QSAR from 2D to 3D and 4D methods.

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