Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Enterobacter-osteomyelitis in two neonates (author's transl)].

H von Voss, U Göbel, H Kemperdick

    Klinische Padiatrie
    |September 1, 1975
    PubMed
    Summary

    Two newborns with enterobacter-sepsis and osteomyelitis showed limited response to initial antibiotics. Subsequent Chloramphenicol treatment was effective but carried risks, including reversible bone marrow suppression in one infant.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Acoustic reflexes of children with and without central auditory processing disorders].

    HNO·2016
    Same author

    [The agar diffusion method. Round table discussion on the methods and indications for determining blood levels of aminoglycosides].

    Infection·2016
    Same author

    [MR imaging in congenital disorders of the brain].

    Der Nervenarzt·2007
    Same author

    [MR imaging in congenital disorders of the brain].

    Der Radiologe·2005
    Same author

    [From knowledge to practice. Progress in particular diseases. 1904].

    Zeitschrift fur arztliche Fortbildung und Qualitatssicherung·2004
    Same author

    Human motor development and hand laterality: a kinematic analysis of drawing movements.

    Neuroscience letters·2000

    Area of Science:

    • Neonatal Medicine
    • Infectious Diseases
    • Pediatric Pharmacology

    Background:

    • Enterobacter sepsis is a serious infection in neonates.
    • Osteomyelitis can be a complication of neonatal sepsis.
    • Initial antibiotic resistance is a growing concern in treating neonatal infections.

    Observation:

    • Two neonates presented with enterobacter-sepsis and subsequent osteomyelitis.
    • Standard antibiotic treatments (Gentamycin, Chepazolin) were ineffective.
    • Chloramphenicol was used as a salvage therapy, with tetracycline in one case.

    Findings:

    • Chloramphenicol treatment led to clinical improvement in both cases of enterobacter-sepsis and osteomyelitis.
    • One patient experienced dose-dependent, reversible bone marrow suppression attributed to Chloramphenicol.

    Related Experiment Videos

  • This suggests Chloramphenicol can be effective but requires careful monitoring in neonates.

    • Implications:

    • Chloramphenicol may be a viable option for multidrug-resistant neonatal sepsis and osteomyelitis.
    • Neonatal bone marrow response to Chloramphenicol necessitates vigilant monitoring.
    • Further research into optimal dosing and safety profiles of Chloramphenicol in neonates is warranted.