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Related Experiment Videos

Acne mechanica.

O H Mills, A Kligman

    Archives of Dermatology
    |April 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Acne mechanica is skin inflammation caused by physical pressure or friction. This study shows that even sealed skin can trigger acne breakouts from underlying microcomedones.

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    Area of Science:

    • Dermatology
    • Cutaneous Science
    • Acne Pathogenesis

    Background:

    • Acne mechanica is characterized by localized skin exacerbations.
    • It is triggered by physical forces such as pressure, friction, rubbing, squeezing, or stretching.
    • Common examples include friction from clothing, sports equipment, or occupational activities.

    Purpose of the Study:

    • To investigate the role of physical trauma in provoking acne lesions.
    • To demonstrate the induction of inflammatory lesions by occlusive conditions.
    • To explore the link between microcomedone rupture and acne mechanica.

    Main Methods:

    • Review of cases involving physical trauma provoking acne lesions.
    • Experimental induction of acne mechanica by sealing acne-bearing skin with adhesive.

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  • Observation of lesion development over a two-week period.

    • Main Results:

    • Diverse physical traumata, including clothing, sports gear, and occupational pressure, were identified as triggers.
    • Sealing skin under adhesive for two weeks consistently induced new inflammatory lesions.
    • These lesions originated from the rupture of subclinical microcomedones.

    Conclusions:

    • Physical factors like pressure and friction are significant contributors to acne mechanica.
    • Occlusion of the skin can lead to the development of inflammatory acne lesions.
    • Acne mechanica arises from the rupture of microscopic, non-visible comedones due to physical stress.