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Direct synthesis of guanidines using di(imidazole-1-yl)methanimine
Yong-Qian Wu1, Sean K Hamilton, Douglas E Wilkinson
1Department of Research, Guilford Pharmaceuticals, Inc., Baltimore, Maryland 21224, USA. wuy@guilfordpharm.com
The Journal of Organic Chemistry
|October 12, 2002
Abstract:
A direct synthetic approach to guanidine compounds is reported here using di(imidazole-1-yl)methanimine and di(imidazole-1-yl)cyanomethanimine as guanylating reagents.