Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Myelotomy through the years.

P L Gildenberg1

  • 1Houston Stereotactic Center, Houston, Tex. 77030, USA. hsc@stereotactic.net

Stereotactic and Functional Neurosurgery
|October 16, 2002
PubMed
Summary
This summary is machine-generated.

Myelotomy procedures, initially for somatic pain, evolved to effectively treat visceral pain by targeting a newly identified pathway in the dorsal columns. These techniques, including extra-lemniscal and limited myelotomy, offer broad pain relief.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spiegel and Wycis - the early years.

Stereotactic and functional neurosurgery·2002
Same author

Multimodality program involving stereotactic surgery in brain tumor management.

Stereotactic and functional neurosurgery·2001
Same author

Multimodality program involving stereotactic surgery in brain tumor management.

Stereotactic and functional neurosurgery·2001
Same author

Acquired immunodeficiency syndrome and central nervous system tumors.

Journal of neurosurgery·2000
Same author

History of the American Society for Stereotactic and Functional Neurosurgery.

Stereotactic and functional neurosurgery·2000
Same author

Stereotactic biopsy of cerebral lesions in AIDS.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2000
Same journal

Stereotactic Accuracy and Operative Metrics Utilizing the ClearPoint Frameless Intraoperative-CT Image-Based Guidance: A Multi-Institution Analysis.

Stereotactic and functional neurosurgery·2026
Same journal

A Fully MRI-Compatible, Non-Electrical System for Near Real-Time Tremor Monitoring During MR-guided Focused Ultrasound.

Stereotactic and functional neurosurgery·2026
Same journal

Metric choice and programming-output concordance in DBS lead reconstruction robustness.

Stereotactic and functional neurosurgery·2026
Same journal

Trends In Deep Brain Stimulation Surgery in The United States.

Stereotactic and functional neurosurgery·2026
Same journal

Successful MRgFUS VIM Thalamotomy for essential tremor nearby cavernous malformation: image case report.

Stereotactic and functional neurosurgery·2026
Same journal

Deep Brain Stimulation for Sleep-Wake Regulation: A Narrative Review.

Stereotactic and functional neurosurgery·2026
See all related articles

Area of Science:

  • Neurosurgery
  • Pain Management
  • Neuroanatomy

Background:

  • Myelotomy was initially developed to alleviate somatic pain by severing spinothalamic tract fibers.
  • Early observations indicated pain relief extended beyond targeted dermatomes, suggesting broader mechanisms.
  • Various myelotomy techniques emerged, including stereotactic and non-stereotactic approaches, for different pain types.

Purpose of the Study:

  • To review the historical development and evolving understanding of myelotomy procedures for pain management.
  • To highlight the identification of a specific neural pathway responsible for pain relief across different myelotomy techniques.
  • To emphasize the effectiveness of myelotomy, particularly limited myelotomy, in managing visceral pain.

Main Methods:

  • Historical review of myelotomy procedures and their outcomes.

Related Experiment Videos

  • Discussion of anatomical findings identifying the ventromedial dorsal column pathway.
  • Correlation of surgical techniques with observed pain relief patterns.
  • Main Results:

    • Myelotomy procedures, despite variations, consistently target a specific pathway in the dorsal columns.
    • Extra-lemniscal myelotomy, limited myelotomy, and thoracic dorsal column midline myelotomy all provide pain relief.
    • These procedures are particularly effective for visceral pain, especially in cancer patients.

    Conclusions:

    • All described myelotomy techniques interrupt the same newly defined ventromedial dorsal column pathway.
    • The historical progression of myelotomy demonstrates a growing understanding of pain pathways and surgical targets.
    • Myelotomy remains a valuable intervention for refractory visceral pain.