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Related Experiment Videos

Stereotactic Accuracy and Operative Metrics Utilizing the ClearPoint Frameless Intraoperative-CT Image-Based

Matthan Tharakan, Kishore Balasubramanian, Rohan Aggarwal

    Stereotactic and Functional Neurosurgery
    |June 29, 2026
    PubMed
    Summary

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    This summary is machine-generated.

    ClearPoint Software v3.0 using intraoperative CT achieved submillimeter accuracy for deep brain stimulation lead placement in standard operating rooms. This frameless system offers a simpler workflow compared to MRI-guided stereotaxy.

    Area of Science:

    • Neurosurgery
    • Medical Imaging
    • Neurological Devices

    Background:

    • MRI-guided stereotaxy offers high accuracy but requires specialized MRI suites and complex workflows.
    • ClearPoint Software v3.0 enables stereotactic procedures in conventional operating rooms using intraoperative CT (iCT).

    Purpose of the Study:

    • To evaluate the stereotactic accuracy and operative efficiency of the ClearPoint frameless iCT image-guided system for deep brain stimulation (DBS) lead implantation.

    Main Methods:

    • A multi-center retrospective review of 23 consecutive DBS lead placement procedures using ClearPoint Software v3.0 was conducted across 7 sites.
    • Primary outcomes assessed were radial targeting error and operative duration.

    Main Results:

    Related Experiment Videos

  • High targeting accuracy was achieved with a median radial error of 0.20 mm on both sides.
  • Median operative duration was 203 minutes, with a median of 6 intraoperative scans and 2 adjustments per side.

    • Conclusions:

    • The ClearPoint frameless iCT workflow demonstrated consistent submillimeter accuracy for DBS lead placement.
    • This system offers favorable operative metrics in a standard operating room setting, simplifying the stereotactic procedure.