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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Surgical approaches to malignant melanoma. Practical guidelines
1Division of Surgical Oncology, Department of Surgery, New York University School of Medicine, 530 First Avenue, Suite 7G, New York, NY 10016, USA. richard.shapiro@med.nyu.edu
Abstract:
Practical guidelines for the surgical approach to malignant melanoma are discussed in detail. Topics include diagnosis and proper biopsy technique; the appropriate preoperative metastatic workup; width of excision margins; treatment of the regional lymph nodes including cutaneous lymphoscintigraphy, intraoperative lymphatic mapping, and sentinel lymphadenectomy; postoperative follow-up schedules; management of local recurrence including surgical resection, isolated limb perfusion, intralesional therapy, adjuvant immunotherapy; management of special clinical situations including subungal melanoma, plantar melanoma, melanoma on the face, melanoma in pregnancy, and the treatment of lesions of uncertain diagnosis.

