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Updated: Sep 28, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Follicular baso-squamous melanocytic tumour of the skin
L Riccioni1, G Cenacchi, T Ragazzini
1Section of Anatomic Pathology, M Bufalini Hospital, Cesena, Italy.
Aims:
We describe a previously unrecognized pigmented tumour of the skin and suggest a possible relationship with the follicular bulb.
Methods And Results:
A pigmented epithelial neoplasm clinically simulating a malignant melanoma of the skin was present in a 92-year-old woman, on her left leg. It was composed of three cell types: squamous cells with trichilemmal keratinization, basaloid cells and dendritic melanocytes. The presence of three cell types was confirmed by immunohistochemistry and electron microscopy.
Conclusions:
The tumour showed differentiation towards the hair follicular bulb and the descriptive term of follicular baso-squamous melanocytic tumour is suggested.
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