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Hyaline-vascular type Castleman's disease involving both orbits

Keun-Sung Park1, You-Jin Choi, Kyu-Sang Song

  • 1Department of Ophthalmology, College of Medicine, Chungnam National University, Taejon, South Korea. ksparkmd@cnu.ac.kr

Insights

Hyaline-vascular Castleman's disease (CD) presented as an isolated upper eyelid mass in an 18-year-old woman. Surgical excision was curative, highlighting CD as a rare cause of orbital tumors.

Area of Science:

  • Ophthalmology
  • Oncology
  • Pathology

Background:

  • Castleman's disease (CD) is a rare lymphoproliferative disorder.
  • Hyaline-vascular type is the most common subtype of CD.
  • CD can present with diverse clinical manifestations.

Observation:

  • An 18-year-old woman presented with bilateral upper eyelid swelling.
  • Initial examination revealed an isolated orbital mass.
  • The patient underwent surgical excision of the mass.

Findings:

  • Histopathology confirmed hyaline-vascular type Castleman's disease.
  • The patient remained asymptomatic one year post-surgery.
  • No clinical or laboratory abnormalities were detected post-treatment.

Implications:

  • Castleman's disease should be considered in the differential diagnosis of orbital masses.
  • Early diagnosis and treatment, such as surgical excision, can lead to favorable outcomes.
  • Orbital involvement of CD warrants ophthalmological attention.
Abstract

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