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System for Focal, Closed-System Central Nervous System Injury
Published on: November 29, 2024
Photoonycholysis
1Nail Disease Centre, 42, rue des Serbes, 06400 Cannes, France. baran.r@club-internet.fr
Background/Purpose:
Photoonycholysis may be seen as a part of Segal's triad, photosensitivity followed by discoloration of the nails and onycholysis. But the latter may also appear, independently, in the absence of photosensitive reaction elsewhere.
Methods:
Photoonycholysis may result from drug intake, porphyria cutanea tarda, erythropoietic porphyria, erythropoietic protoporphyria, variegate porphyria and pseudoporphyria. Rarely, spontaneous photoonycholysis may be observed.
Results:
Four distinct subtypes have been recorded without relationship between the responsible drugs and the different clinical varieties of photoonycholysis. Primary photohemorrhage can occur; it can also be associated with polydactylous photoonycholysis type III.
Conclusion:
The inability to reproduce photoonycholysis experimentally should be emphasized.
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