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Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Metabolic abnormalities in HIV disease and injection drug use
1The John Hopkins University School of Medicine, Baltimore, Maryland, USA. adobs@jhu.edu
Abstract:
HIV infection is associated with a number of adverse consequences, including metabolic disorders. This article reviews disorders such as wasting, lipid metabolism disorders (including fat redistribution or dyslipidemia), glucose abnormalities, bone disease, and endocrine disorders such as hypogonadism in the presence of HIV infection and/or drug abuse. The issues covered are current estimations of prevalence, risk factors, underlying pathophysiology, diagnosis, and interventions (prevention and treatment) for metabolic complications of HIV and drug abuse.
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