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Extrapulmonary tuberculosis in surgical specimens.

M S I Talukder1, M H Huq, A Haque

  • 1Department of Pathology, MMC, Mymensingh. sadequel@bttb.net.bd

Mymensingh Medical Journal : MMJ
|October 25, 2002
PubMed
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Extrapulmonary tuberculosis (EPTB) is common in surgical specimens, particularly affecting lymph nodes in early adulthood. This study highlights cervical lymphadenitis as the most frequent site for EPTB in the examined population.

Area of Science:

  • Pathology
  • Microbiology
  • Public Health

Background:

  • Tuberculosis is a prevalent condition, with extrapulmonary manifestations frequently encountered in surgical pathology.
  • Understanding the distribution of extrapulmonary tuberculosis (EPTB) is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate the organ distribution of extrapulmonary tuberculosis (EPTB) using surgical specimens.
  • To identify common sites and demographic patterns of EPTB in a specific region.

Main Methods:

  • Histological examination of 103 surgical specimens diagnosed with tubercular lesions.
  • Analysis of specimen origin, patient demographics (age, sex), and lesion location.

Main Results:

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  • Lymph node involvement was the most common EPTB site (84.9%), predominantly cervical lymphadenitis (89.7% of lymph node cases).
  • Other affected organs included intestine (8.7%), bone (1.9%), and reproductive organs (epididymis, fallopian tube).
  • EPTB was more prevalent in females (M:F = 1:1.8) and young adults (median age 28 years).

    • Conclusions:

    • Extrapulmonary tuberculosis is common in early adulthood, with a female predominance in this study's population.
    • Cervical lymph nodes are the most frequent site for EPTB, underscoring the importance of considering lymphadenitis in differential diagnoses.
    • Histological evaluation of surgical specimens is vital for accurate EPTB diagnosis and understanding its epidemiological patterns.