Iodinated Contrast Induced Parotitis: A Case Report

Area of Science:

• Cardiology
• Radiology
• Endocrinology

Background:

• Iodinated contrast media are frequently used in cardiovascular imaging procedures.
• Parotitis is a known, albeit rare, adverse reaction to iodinated contrast agents.
• This case highlights a potential complication following percutaneous coronary intervention (PCI).

Observation:

• A 70-year-old male with a history of hypertension, diabetes mellitus, and dyslipidemia presented with chest pain and shortness of breath.
• The patient had recently recovered from COVID-19 and had undergone PCI two years prior.
• Following coronary angiography, the patient developed bilateral parotitis.

Findings:

• Diagnostic workup revealed Non-ST-elevation myocardial infarction (NSTEMI) with impaired left ventricular function (ALVF).
• Electrocardiogram showed a bi-fascicular block, and echocardiogram indicated hypokinesis of the inferior and inferior-lateral walls.
• High-sensitivity Troponin I levels were elevated, while serum creatinine remained normal.

Implications:

• This case underscores the importance of recognizing parotitis as a potential adverse effect of iodinated contrast agents in patients undergoing cardiovascular procedures.
• Conservative management was effective in resolving the parotitis, suggesting a possible direct toxicity or idiosyncratic reaction to the contrast material.
• Awareness of this complication may aid in timely diagnosis and appropriate patient management, potentially preventing unnecessary interventions.